Description

(1S)-(2-Fluoro-6-Methoxyphenyl)Ethylamine is a high-purity chiral amine building block of significant importance in modern pharmaceutical synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with specific stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drugs, particularly in areas requiring fluorinated and methoxy-substituted aromatic scaffolds.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used in catalytic asymmetric reactions to introduce the (1S)-configured ethylamine moiety into target molecules.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in enantioselective transformations.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore the impact of fluorinated aromatic systems on drug potency and selectivity.
• Process Chemistry & Scale-up: Used in the optimization and pilot-scale production of candidate drugs before commercial manufacturing.

Basic Information

Product Name	(1S)-(2-Fluoro-6-Methoxyphenyl)Ethylamine
CAS No.	870849-68-6
Molecular Formula	C9H12FNO
Molecular Weight	169.20 g/mol
Synonyms	(1S)-1-(2-Fluoro-6-methoxyphenyl)ethanamine; (S)-1-(2-Fluoro-6-methoxyphenyl)ethylamine; (S)-α-Methyl-2-fluoro-6-methoxybenzylamine; (S)-1-(2-Fluoro-6-methoxyphenyl)ethan-1-amine; (S)-2-Fluoro-6-methoxy-α-methylbenzylamine; (S)-1-Aminoethyl-2-fluoro-6-methoxybenzene; (S)-1-(2-Fluoro-6-methoxyphenyl)ethylamine
EINECS	Contact for details

Quality Control

Our (1S)-(2-Fluoro-6-Methoxyphenyl)Ethylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with high-grade pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.