Description

1-(2,3-Difluorophenyl)Ethan-1-Amine is a high-purity fluorinated aromatic amine building block of significant importance in modern synthetic chemistry. This compound serves as a critical intermediate for the development of advanced pharmaceuticals and agrochemicals, where its difluorophenyl moiety is leveraged to modulate biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where fluorine substitution enhances efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for creating fluorescent tags and molecular probes for biochemical research and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up campaigns in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	1-(2,3-Difluorophenyl)Ethan-1-Amine
CAS No.	870849-27-7
Molecular Formula	C8H9F2N
Molecular Weight	157.16 g/mol
Synonyms	1-(2,3-Difluorophenyl)ethanamine; α-Methyl-2,3-difluorobenzylamine; 1-Aminoethyl-2,3-difluorobenzene; 2,3-Difluoro-α-methylbenzylamine; (2,3-Difluorophenyl)ethylamine; 1-(2,3-Difluorophenyl)ethylamine; 2,3-DFPEA; 870849-27-7
EINECS	Contact for details

Quality Control

Our 1-(2,3-Difluorophenyl)Ethan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%
Specific Rotation (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.