Description

5-Bromo-4-Chloro-7-Isopropyl-7H-Pyrrolo[2,3-D]Pyrimidine is a high-value halogenated pyrrolopyrimidine derivative, a crucial building block in modern pharmaceutical and agrochemical research. Its core value lies in its versatile scaffold, which serves as a key intermediate for synthesizing targeted small molecule inhibitors and active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries, particularly for developing kinase inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Agrochemical Active Ingredient Synthesis: Used in the development of new generation herbicides and fungicides.
• Biochemical Research: Serves as a versatile scaffold for probing enzyme activity and structure-activity relationships (SAR).
• Chemical Biology Probes: Utilized in the creation of labeled compounds for target identification and validation studies.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial manufacturing of APIs.
• Custom Synthesis & Contract Manufacturing: A key starting material for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical services.

Basic Information

Product Name	5-Bromo-4-Chloro-7-Isopropyl-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	870706-48-2
Molecular Formula	C9H9BrClN3
Molecular Weight	274.54 g/mol
Synonyms	5-Bromo-4-chloro-7-(propan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 5-bromo-4-chloro-7-(1-methylethyl)-; 5-Bromo-4-chloro-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine; 870706-48-2; 4-Chloro-5-bromo-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine; 7-Isopropyl-5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloro-7-Isopropyl-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.