Description

6H-[1,2,4]Triazolo[4,3-A][1,5]Benzodiazepine-6-Acetamide, 4,5-Dihydro-4-(1H-Indol-3-Ylmethyl)-n-(1-Methylethyl)-5-Oxo-1-Phenyl-n-(Phenylmethyl)-, (-)- is a complex heterocyclic compound belonging to the triazolobenzodiazepine class, serving as a critical advanced pharmaceutical intermediate. Its intricate molecular architecture makes it a valuable scaffold for research and development in medicinal chemistry, particularly for targeting specific neurological pathways. This high-purity compound is essential for pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Preclinical Development: Serves as a critical material for pharmacokinetic, pharmacodynamic, and toxicology studies during early-stage drug development.
• Reference Standard: High-purity grade suitable for use as an analytical reference standard in quality control and regulatory submissions.
• Chemical Biology Probes: Utilized in the development of specialized probes for studying receptor-ligand interactions and enzyme functions.
• Fine Chemical Synthesis: Intermediate for the custom synthesis of more complex, target-specific molecules for specialized research applications.

Basic Information

Product Name	6H-[1,2,4]Triazolo[4,3-A][1,5]Benzodiazepine-6-Acetamide, 4,5-Dihydro-4-(1H-Indol-3-Ylmethyl)-n-(1-Methylethyl)-5-Oxo-1-Phenyl-n-(Phenylmethyl)-, (-)-
CAS No.	870615-40-0
Molecular Formula	C37H35N5O2
Molecular Weight	581.71 g/mol
Synonyms	(-)-4,5-Dihydro-4-(1H-indol-3-ylmethyl)-N-isopropyl-5-oxo-1-phenyl-N-(phenylmethyl)-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine-6-acetamide; UNII-6Y1V05TZ6P; 6H-[1,2,4]Triazolo[4,3-a][1,5]benzodiazepine-6-acetamide, 4,5-dihydro-4-(1H-indol-3-ylmethyl)-N-(1-methylethyl)-5-oxo-1-phenyl-N-(phenylmethyl)-, (-)-; 870615-40-0; Adinazolam related compound; Triazolobenzodiazepine derivative.
EINECS	Contact for details

Quality Control

Our 6H-[1,2,4]Triazolo[4,3-A][1,5]Benzodiazepine-6-Acetamide derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed under an inert atmosphere if specified and kept in a desiccator to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.