Description

4-Fluoro-2-Methoxybenzylamine is a versatile fluorinated aromatic amine building block of significant importance in modern synthetic chemistry. Its molecular structure, featuring both a fluorine atom and a methoxy group ortho to the amine-substituted benzyl position, makes it a key intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors. It serves as a critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology & Proteomics: Utilized as a reactive handle for bioconjugation and the development of chemical probes for studying biological systems.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	4-Fluoro-2-Methoxybenzylamine
CAS No.	870563-60-3
Molecular Formula	C8H10FNO
Molecular Weight	155.17 g/mol
Synonyms	(4-Fluoro-2-methoxyphenyl)methanamine; 1-(4-Fluoro-2-methoxyphenyl)methanamine; 2-Methoxy-4-fluorobenzylamine; 4-Fluoro-2-methoxybenzenemethanamine; 4-Fluoro-o-anisylamine; Benzenemethanamine, 4-fluoro-2-methoxy-; α-Amino-4-fluoro-2-methoxytoluene
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methoxybenzylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where required, ensuring reliability for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.