Description

Phenol, 2-(Aminomethyl)-5-Fluoro-, Hydrochloride (1:1) is a specialized fluorinated phenol derivative with an aminomethyl functional group, presented as its hydrochloride salt for enhanced stability and handling. This compound serves as a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily required by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and material science sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and pesticides with fluorinated backbones for improved efficacy and environmental profile.
• Organic Synthesis Reagent: Used in medicinal chemistry and process chemistry for introducing the 2-(aminomethyl)-5-fluorophenol moiety into more complex molecular architectures.
• Bioconjugation & Probe Development: Utilized in biochemical research for labeling and probe synthesis due to its reactive amine and phenol groups.
• Material Science Research: Monomer or modifier in the development of specialty polymers and advanced materials with specific functional properties.

Basic Information

Product Name	Phenol, 2-(Aminomethyl)-5-Fluoro-, Hydrochloride (1:1)
CAS No.	870562-95-1
Molecular Formula	C7H9FNO • HCl
Molecular Weight	177.61 g/mol (Free base) / 214.06 g/mol (HCl salt)
Synonyms	5-Fluoro-2-(aminomethyl)phenol hydrochloride; 2-(Aminomethyl)-5-fluorophenol hydrochloride; (5-Fluoro-2-hydroxybenzyl)amine hydrochloride; 5-Fluoro-2-hydroxybenzylamine hydrochloride; 2-Hydroxy-5-fluorobenzylamine hydrochloride; 5-Fluoro-salicylamine hydrochloride; 870562-95-1
EINECS	Contact for details

Quality Control

Our Phenol, 2-(Aminomethyl)-5-Fluoro-, Hydrochloride (1:1) is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0% - 103.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.