Description

5-(4-Fluoro-Phenyl)-7-Pentafluoroethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carbonyl Chloride is a high-value, multi-fluorinated heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fluorinated pyrazolopyrimidine core imparts desirable metabolic stability and bioavailability. It is primarily targeted at the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of next-generation fluorinated compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of novel herbicides and fungicides, leveraging the fluorine atoms for enhanced efficacy and environmental profile.
• Material Science Research: Serves as a precursor for fluorinated organic electronic materials and liquid crystals.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and probes for studying biological mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke chemical synthesis projects.

Basic Information

Product Name	5-(4-Fluoro-Phenyl)-7-Pentafluoroethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carbonyl Chloride
CAS No.	870261-22-6
Molecular Formula	C₁₇H₇ClF₆N₃O
Molecular Weight	430.70 g/mol
Synonyms	5-(4-Fluorophenyl)-7-(pentafluoroethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride; 7-(Pentafluoroethyl)-5-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride; 870261-22-6; Pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride, 5-(4-fluorophenyl)-7-(pentafluoroethyl)-; 5-(4-Fluorophenyl)-7-(1,1,2,2,2-pentafluoroethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 5-(4-Fluoro-Phenyl)-7-Pentafluoroethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carbonyl Chloride adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.