Description

4-(2-Chloropyridin-3-Yl)Pyrimidin-2-Amine CAS NO 870221-49-1 is a high-purity, heterocyclic organic compound featuring a pyrimidine core linked to a chloropyridine moiety. This specific molecular architecture makes it a critical intermediate in advanced organic synthesis, particularly for constructing complex pharmacologically active molecules. It is primarily required by pharmaceutical R&D and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic structure.
• Material Science: Serves as a precursor for organic electronic materials and ligands in catalytic systems.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and discovery chemistry.
• Custom Synthesis: A starting material for the contract manufacturing of complex, proprietary molecules for clients.

Basic Information

Product Name	4-(2-Chloropyridin-3-Yl)Pyrimidin-2-Amine
CAS No.	870221-49-1
Molecular Formula	C9H7ClN4
Molecular Weight	206.63 g/mol
Synonyms	4-(2-Chloro-3-pyridinyl)-2-pyrimidinamine; 2-Amino-4-(2-chloro-3-pyridinyl)pyrimidine; 4-(2-Chloropyridin-3-yl)pyrimidin-2-ylamine; 4-(2-Chloro-3-pyridyl)pyrimidin-2-amine; 870221-49-1; 4-(2-Chloro-3-pyridinyl)-2-aminopyrimidine
EINECS	Contact for details

Quality Control

Our production of 4-(2-Chloropyridin-3-Yl)Pyrimidin-2-Amine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.