Description

2-Hydrazino-4-Phenyl-6-(Trifluoromethyl)Pyrimidine is a specialized heterocyclic building block featuring a reactive hydrazino group and a trifluoromethyl substituent. This compound matters for its role as a key intermediate in the synthesis of high-value pharmaceuticals and advanced agrochemicals, where the CF3 group is prized for enhancing metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel pyrimidine-based scaffolds.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Serves as a precursor for developing novel herbicides, fungicides, and insecticides that leverage the bioactivity of the pyrimidine core.
• Chemical Research & Development: Used as a versatile building block for creating libraries of novel heterocyclic compounds in medicinal chemistry.
• Material Science Precursor: Potential use in the development of organic electronic materials and metal-organic frameworks (MOFs) due to its functionalized aromatic system.

Basic Information

Product Name	2-Hydrazino-4-Phenyl-6-(Trifluoromethyl)Pyrimidine
CAS No.	869952-73-8
Molecular Formula	C11H9F3N4
Molecular Weight	254.21 g/mol
Synonyms	4-Phenyl-6-(trifluoromethyl)pyrimidine-2-hydrazine; 2-Hydrazinyl-4-phenyl-6-(trifluoromethyl)pyrimidine; 6-(Trifluoromethyl)-4-phenyl-2-pyrimidinylhydrazine; 869952-73-8; 4-Phenyl-6-trifluoromethyl-2-hydrazinopyrimidine; 2-Hydrazino-4-phenyl-6-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Our 2-Hydrazino-4-Phenyl-6-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.