Description

7-Trifluoromethyl-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure containing a trifluoromethyl group. This compound is of significant value for medicinal chemistry research and development, offering a versatile scaffold for the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical companies and research institutions engaged in the development of new therapeutic agents, particularly in areas such as kinase inhibitors and central nervous system (CNS) drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical development.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the creation of targeted compound libraries.
• Kinase Inhibitor Development: Used in the research and production of potential kinase inhibitors for oncology and inflammatory diseases.
• CNS Drug Discovery: Employed in the design and synthesis of novel compounds targeting neurological and psychiatric disorders.
• Agrochemical Research: Potential intermediate for developing new crop protection agents and herbicides.
• Chemical Biology Probes: Utilized as a starting material for creating probes to study biological pathways and protein functions.

Basic Information

Item	Details
Product Name	7-Trifluoromethyl-4,5,6,7-Tetrahydro-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid
CAS No.	869948-09-4
Molecular Formula	C9H8F3N3O2
Molecular Weight	247.18 g/mol
Synonyms	7-(Trifluoromethyl)-4,5,6,7-tetrahydro-2H-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 7-Trifluoromethyl-4,5,6,7-tetrahydro-2H-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 869948-09-4; Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 4,5,6,7-tetrahydro-7-(trifluoromethyl)-; 7-Trifluoromethyl-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 7-Trifluoromethyl-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and scale-up with custom purity grades to meet specific project requirements from research to commercial production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.