Description

7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its core value lies in its unique pyrazolopyrimidine scaffold functionalized with a trifluoromethyl group, offering enhanced metabolic stability and lipophilicity for the development of novel bioactive molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, serving as a critical intermediate for the synthesis of potential drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of small molecule drug candidates, particularly in oncology, inflammation, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Chemical Biology Probe Development: Serves as a core structure for creating tool compounds to study enzyme function and biological pathways.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials, such as ligands for catalysts or components for organic electronics.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid
CAS No.	869947-41-1
Molecular Formula	C8H4F3N3O2
Molecular Weight	231.13 g/mol
Synonyms	7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid; 7-(Trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinecarboxylic acid; 869947-41-1; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 7-(trifluoromethyl)-; 7-Trifluoromethylpyrazolo[1,5-a]pyrimidine-3-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.