Description

7-Chloromethyl-5-Oxo-4,5-Dihydro-Pyrazolo[1,5-A ]Pyrimidine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is essential for research and development chemists and process scale-up teams in the pharmaceutical and biotechnology sectors seeking to develop new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, particularly those with pyrazolo[1,5-a]pyrimidine scaffolds.
• API Development: Used in research and development for creating new Active Pharmaceutical Ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: A valuable building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry & Scale-up: Employed in route scouting, optimization, and pilot-scale manufacturing of candidate drugs.
• Bioconjugation & Prodrug Synthesis: The carboxylic acid and chloromethyl functional groups offer handles for conjugation, enabling the development of targeted therapies or prodrugs.
• Agrochemical Research: Potential use as an intermediate in the development of new agrochemicals with specific biological activity.

Basic Information

Item	Detail
Product Name	7-Chloromethyl-5-Oxo-4,5-Dihydro-Pyrazolo[1,5-A ]Pyrimidine-2-Carboxylic Acid
CAS No.	869947-01-3
Molecular Formula	C9H6ClN3O3
Molecular Weight	239.61 g/mol
Synonyms	7-(Chloromethyl)-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 2-Pyrazolo[1,5-a]pyrimidinecarboxylic acid, 4,5-dihydro-7-(chloromethyl)-5-oxo-; 869947-01-3; 7-Chloromethyl-5-oxo-4H-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 4,5-Dihydro-7-(chloromethyl)-5-oxopyrazolo[1,5-a]pyrimidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 7-Chloromethyl-5-Oxo-4,5-Dihydro-Pyrazolo[1,5-A ]Pyrimidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.