Description

5-Fluoro-2-(Tetrahydro-Furan-2-Ylmethoxy)-Phenylamine is a specialized aromatic amine derivative featuring a fluorine substituent and a tetrahydrofuran-based ether linkage. This unique molecular structure makes it a valuable high-purity building block for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams requiring precise, high-quality intermediates for complex molecular construction.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	5-Fluoro-2-(Tetrahydro-Furan-2-Ylmethoxy)-Phenylamine
CAS No.	869944-74-1
Molecular Formula	C11H14FNO2
Molecular Weight	211.23 g/mol
Synonyms	5-Fluoro-2-[(oxolan-2-yl)methoxy]aniline; 2-Amino-4-fluoro-1-[(tetrahydro-2-furanyl)methoxy]benzene; 5-Fluoro-2-(tetrahydrofuran-2-ylmethoxy)aniline; 5-Fluoro-2-(tetrahydrofuran-2-ylmethoxy)phenylamine; 869944-74-1; 5-Fluoro-2-(tetrahydrofuran-2-ylmethoxy)benzenamine; 2-(Tetrahydrofuran-2-ylmethoxy)-5-fluoroaniline
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(Tetrahydro-Furan-2-Ylmethoxy)-Phenylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring suitability for demanding pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider the use of desiccants or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.