Description

2-Bromo-5-(Trifluoromethyl)Benzyl Alcohol is a versatile and high-value fluorinated aromatic building block. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique trifluoromethyl and bromo substituents enable precise molecular tuning. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Functional Material Development: Employed in creating specialty polymers, ligands for catalysis, and advanced organic frameworks with tailored properties.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to build complex biaryl structures.

Basic Information

Product Name	2-Bromo-5-(Trifluoromethyl)Benzyl Alcohol
CAS No.	869725-53-1
Molecular Formula	C8H6BrF3O
Molecular Weight	255.04 g/mol
Synonyms	(2-Bromo-5-(trifluoromethyl)phenyl)methanol; α-Bromo-α,α,α-trifluoro-m-tolyl alcohol; 2-Bromo-α,α,α-trifluoro-m-toluyl alcohol; 1-Bromo-4-(hydroxymethyl)-2-(trifluoromethyl)benzene; 2-Bromo-5-(trifluoromethyl)benzenemethanol; Benzyl alcohol, 2-bromo-5-(trifluoromethyl)-; m-Trifluoromethyl-2-bromobenzyl alcohol
EINECS	Contact for details

Quality Control

Our production of 2-Bromo-5-(Trifluoromethyl)Benzyl Alcohol adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.