Description

(5R)-N6-[(5S)-5-Amino-5-Carboxypentyl]-5-Hydroxy-L-Lysine Trihydrochloride is a high-purity, chemically defined derivative of lysine, specifically modified with a hydroxy and an amino-carboxypentyl group. This compound is a critical building block and intermediate in advanced pharmaceutical research, particularly in the synthesis of complex peptides and bioconjugates. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require precise, high-quality intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel therapeutic peptides and peptidomimetics.
• Bioconjugation Chemistry: Used in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems due to its functionalizable amine and carboxyl groups.
• Biochemical Research: Serves as a specialized substrate or inhibitor in enzymatic studies and proteomics research.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Precursor for Linker Molecules: Utilized in the design and synthesis of sophisticated chemical linkers for biopharmaceutical applications.

Basic Information

Product Name	(5R)-N6-[(5S)-5-Amino-5-Carboxypentyl]-5-Hydroxy-L-Lysine Trihydrochloride
CAS No.	869184-37-2
Molecular Formula	C13H28N3O5 • 3HCl
Molecular Weight	426.15 g/mol (Free base: 306.38 g/mol)
Synonyms	5-Hydroxy-N6-[(5S)-5-amino-5-carboxypentyl]-L-lysine trihydrochloride; (5R)-5-Hydroxy-N-[(5S)-5-amino-5-carboxypentyl]-L-lysine trihydrochloride; 5-Hydroxy-L-lysine derivative trihydrochloride; N6-(5-Amino-5-carboxypentyl)-5-hydroxy-L-lysine trihydrochloride; (2S,5R)-2,6-Diamino-5-hydroxyhexanoic acid N6-[(5S)-5-amino-5-carboxypentyl] trihydrochloride
EINECS	Contact for details

Quality Control

Our (5R)-N6-[(5S)-5-Amino-5-Carboxypentyl]-5-Hydroxy-L-Lysine Trihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.