Description

(5S)-N6-[(5S)-5-Amino-5-Carboxypentyl]-5-Hydroxy-L-Lysine Trihydrochloride is a high-purity, chemically defined derivative of lysine, specifically modified with a 5-hydroxy and an additional amino-carboxypentyl group. This compound is of significant interest for advanced research and development in pharmaceutical chemistry and biochemistry, serving as a critical building block or reference standard. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications requiring precise molecular structures. The trihydrochloride salt form enhances its stability and solubility for experimental use.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents, particularly for metabolic or enzyme-targeted drugs.
• Biochemical Research: Used as a substrate, inhibitor, or standard in enzymatic studies and metabolic pathway analysis due to its modified lysine structure.
• Peptide Synthesis: Acts as a specialized, protected amino acid derivative for the solid-phase or solution-phase synthesis of complex peptides and peptidomimetics.
• Reference Standard: Employed in analytical laboratories as a high-purity certified reference material (CRM) for method development, validation, and quality control.
• Proteomics & Cell Biology: May be used in studies investigating post-translational modifications, protein-protein interactions, or as a component in specialized cell culture media.
• Academic Research: A valuable tool for universities and research institutes exploring amino acid chemistry, drug discovery, and molecular biology.

Basic Information

Product Name	(5S)-N6-[(5S)-5-Amino-5-Carboxypentyl]-5-Hydroxy-L-Lysine Trihydrochloride
CAS No.	869111-61-5
Molecular Formula	C17H34N4O6 • 3HCl
Molecular Weight	~ 536.85 g/mol (Free base: 390.48)
Synonyms	5-Hydroxy-N6-[(5S)-5-amino-5-carboxypentyl]-L-lysine trihydrochloride; (2S)-2-Amino-6-{[(1S)-5-amino-1-carboxypentyl]amino}-5-hydroxyhexanoic acid trihydrochloride; 5-Hydroxy-L-lysine derivative trihydrochloride; N6-(5-Amino-5-carboxypentyl)-5-hydroxy-L-lysine 3HCl; L-Lysine, N6-[(5S)-5-amino-5-carboxypentyl]-5-hydroxy-, trihydrochloride, (5S)-; A specialized hydroxylysine analog trihydrochloride
EINECS	Contact for details

Quality Control

Our (5S)-N6-[(5S)-5-Amino-5-Carboxypentyl]-5-Hydroxy-L-Lysine Trihydrochloride is manufactured under controlled conditions to ensure high chemical purity and batch-to-batch consistency. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each batch, documenting identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support its use in research and development phases of pharmaceutical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent exposure to atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.