Description

4-Chloro-6-(2-Fluoro-4-Nitrophenoxy)Pyrimidine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its unique molecular architecture, which incorporates reactive halogen and nitro substituents on an aromatic pyrimidine scaffold, making it a versatile precursor for constructing complex molecules. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel small-molecule therapeutics, particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Research: Serves as a critical building block for developing next-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Used in the research and development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology: Employed as a molecular probe or a linker in bioconjugation chemistry for studying biological processes.
• Custom Synthesis: An essential starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.
• Academic Research: Utilized in universities and research institutes for methodological studies in heterocyclic and nucleophilic aromatic substitution chemistry.

Basic Information

Product Name	4-Chloro-6-(2-Fluoro-4-Nitrophenoxy)Pyrimidine
CAS No.	868733-15-7
Molecular Formula	C10H5ClFN3O3
Molecular Weight	269.62 g/mol
Synonyms	4-Chloro-6-[(2-fluoro-4-nitrophenyl)oxy]pyrimidine; 6-(2-Fluoro-4-nitrophenoxy)-4-chloropyrimidine; Pyrimidine, 4-chloro-6-[(2-fluoro-4-nitrophenyl)oxy]-; 4-Chloro-6-(2-fluoro-4-nitro-phenoxy)-pyrimidine; 868733-15-7; 4-Chloro-6-(2-fluoro-4-nitrophenoxy)pyrimidine; 4-Chloro-6-(2-fluoro-4-nitro-phenoxy)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(2-Fluoro-4-Nitrophenoxy)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.