Description

4-Bromo-2-Iodo-5-(Trifluoromethyl)Aniline is a highly functionalized aniline derivative, serving as a critical multi-halogenated building block in advanced organic synthesis. Its value lies in the strategic placement of bromine, iodine, and trifluoromethyl groups on the aromatic ring, enabling precise cross-coupling reactions and the introduction of fluorine-containing motifs. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting CNS disorders and oncology.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Material Science: Used in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Serves as a versatile substrate for Suzuki, Stille, and Sonogashira couplings due to the reactive bromine and iodine substituents.
• Fluorine Chemistry: Integral for introducing the trifluoromethyl group into complex molecules, a common strategy to modulate lipophilicity and metabolic stability.
• Chemical Research: Valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	4-Bromo-2-Iodo-5-(Trifluoromethyl)Aniline
CAS No.	868692-81-3
Molecular Formula	C7H4BrF3IN
Molecular Weight	375.92 g/mol
Synonyms	4-Bromo-2-iodo-5-(trifluoromethyl)benzenamine; 2-Iodo-4-bromo-5-(trifluoromethyl)aniline; 5-Amino-2-bromo-4-iodobenzotrifluoride; Benzenamine, 4-bromo-2-iodo-5-(trifluoromethyl)-; 868692-81-3; 4-Br-2-I-5-CF3-Aniline
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Iodo-5-(Trifluoromethyl)Aniline is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.