Description

Colivelin CAS NO 867021-83-8 is a synthetic peptide known for its neuroprotective properties, functioning as a potent activator of the STAT3 signaling pathway. This compound is of significant interest for research into neurodegenerative diseases and cellular aging processes. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in neuroscience, drug discovery, and life science studies.

Application

• Neuroscience Research: Investigated for its potential to protect neurons from apoptosis, relevant to studies on Alzheimer's disease, Parkinson's disease, and other neurodegenerative conditions.
• Drug Discovery & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in preclinical studies for novel neuroprotective therapeutics.
• Cell Biology Studies: Used as a research tool to study the STAT3-mediated signaling cascade and its role in cell survival, proliferation, and differentiation.
• Anti-Aging Research: Employed in biochemical assays to explore mechanisms related to cellular senescence and lifespan extension.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in neurobiology and peptide pharmacology.

Basic Information

Product Name	Colivelin
CAS No.	867021-83-8
Molecular Formula	C152H246N44O43
Molecular Weight	3359.8 g/mol
Synonyms	Colivelin; H2N-SALLRSIPA-COOH; STAT3 Activator Peptide; Humanin Derivative; Neuroprotective Peptide; STAT3-activating Peptide; SALLRSIPA; CAS 867021-83-8
EINECS	Contact for details

Quality Control

Our Colivelin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, allow the vial to equilibrate to room temperature before opening to prevent condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.