Description

6-Chloro-N4-[3,5-Difluoro-4-[(3-Methyl-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Oxy]Phenyl]-2,4-Pyrimidinediamine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial interest for its critical role in the research and development of novel, targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel kinase inhibitors and other targeted small-molecule drugs.
• Oncology Research: Used in preclinical and clinical research for developing potential anti-cancer therapeutics.
• Biochemical Research: Serves as a reference standard or a probe compound in biochemical and pharmacological studies.
• Process Development: Employed in scaling up and optimizing synthetic routes for complex drug candidates in pilot plants.
• Custom Synthesis: A starting material for the custom synthesis of more complex derivatives for structure-activity relationship (SAR) studies.

Basic Information

Product Name	6-Chloro-N4-[3,5-Difluoro-4-[(3-Methyl-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Oxy]Phenyl]-2,4-Pyrimidinediamine
CAS No.	867017-68-3
Molecular Formula	C18H13ClF2N6O
Molecular Weight	402.79 g/mol
Synonyms	6-Chloro-N4-(3,5-difluoro-4-((3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)pyrimidine-2,4-diamine; 6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine; CAS 867017-68-3; 2,4-Pyrimidinediamine, 6-chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-; 6-Chloro-N4-(3,5-difluoro-4-((3-methyl-7-azaindol-4-yl)oxy)phenyl)pyrimidine-2,4-diamine
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and traceability. Quality is verified through advanced analytical techniques including HPLC, LC-MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.