Description

4-Fluoro-2-Hydroxyphenacyl Bromide is a specialized brominated phenacyl derivative featuring a fluorine substituent, serving as a valuable synthetic intermediate. This compound is significant for its role in constructing complex molecular architectures, particularly in the development of pharmaceuticals and advanced organic materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological and inflammatory pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Photoactivatable Protecting Group Precursor: Serves as a precursor for developing caged compounds and photolabile protecting groups in biochemical research.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides and fungicides with enhanced efficacy.
• Ligand and Catalyst Development: Useful for synthesizing specialized ligands for metal catalysis and organocatalysts.
• Material Science: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.

Basic Information

Product Name	4-Fluoro-2-Hydroxyphenacyl Bromide
CAS No.	866863-55-0
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	2-Bromo-1-(4-fluoro-2-hydroxyphenyl)ethan-1-one; 1-(4-Fluoro-2-hydroxyphenyl)-2-bromoethanone; 4-Fluoro-2-hydroxy-α-bromoacetophenone; 2-Bromo-4'-fluoro-2'-hydroxyacetophenone; α-Bromo-4-fluoro-2-hydroxyacetophenone; 4-Fluoro-2-hydroxy phenacyl bromide; 866863-55-0; 4-Fluoro-2-Hydroxy Phenacyl Bromide
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Hydroxyphenacyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.