Description

(E)-Methyl 3-(Pyrimidin-5-Yl)Acrylate CAS NO 866621-24-1 is a high-purity, versatile chemical building block featuring a conjugated acrylate ester linked to a pyrimidine heterocycle. This compound is valued for its role as a key synthetic intermediate in the development of advanced pharmaceutical compounds and functional materials. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that incorporate the pyrimidine pharmacophore.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialty polymers with tailored optical or electronic properties.
• Chemical Synthesis: Employed in organic synthesis for Michael addition reactions, cycloadditions, and as a precursor for more complex heterocyclic systems.
• Life Science Research: Utilized in academic and industrial R&D for probing biological pathways and developing biochemical probes.

Basic Information

Product Name	(E)-Methyl 3-(Pyrimidin-5-Yl)Acrylate
CAS No.	866621-24-1
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	Methyl (E)-3-(pyrimidin-5-yl)acrylate; Methyl 3-(5-pyrimidinyl)-2-propenoate; (E)-Methyl 3-(5-pyrimidinyl)acrylate; 5-Pyrimidineacrylic acid methyl ester; Methyl trans-3-(pyrimidin-5-yl)acrylate; 2-Propenoic acid, 3-(5-pyrimidinyl)-, methyl ester, (E)-; Methyl 3-(pyrimidin-5-yl)acrylate
EINECS	Contact for details

Quality Control

Our (E)-Methyl 3-(Pyrimidin-5-Yl)Acrylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.