Description

2,3-Difluorophenylacetaldehyde is a versatile fluorinated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the phenyl ring, which can dramatically influence the electronic properties, metabolic stability, and binding affinity of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it serves as a key precursor for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) agents, kinase inhibitors, and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where fluorine incorporation enhances bioactivity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated mesogens and organic light-emitting diode (OLED) materials, improving charge transport and thermal stability.
• Fluorinated Polymer Chemistry: Incorporated into specialty polymers to modify surface properties, chemical resistance, and optical characteristics.
• Chemical Research & Development: A valuable reagent for exploring new fluorination methodologies and structure-activity relationships (SAR) in medicinal chemistry.
• Flavor & Fragrance Chemistry: Potential intermediate for creating unique, stable aromatic compounds in high-value fragrance applications.

Basic Information

Product Name	2,3-Difluorophenylacetaldehyde
CAS No.	866342-07-6
Molecular Formula	C8H6F2O
Molecular Weight	156.13 g/mol
Synonyms	2,3-Difluorobenzeneacetaldehyde; (2,3-Difluorophenyl)acetaldehyde; 2-(2,3-Difluorophenyl)acetaldehyde; 2,3-Difluoro-ω-oxobenzeneethane; 866342-07-6; 2,3-Difluorophenylethanal
EINECS	Contact for details

Quality Control

Our 2,3-Difluorophenylacetaldehyde is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Allow the container to reach room temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.