Description

1,3-Dimethyl-5-[3-(Trifluoromethyl)Benzoyl]-2,4,6(1H,3H,5H)-Pyrimidinetrione is a high-value, specialized heterocyclic compound featuring a trifluoromethylbenzoyl moiety. This structure is of significant interest for its potential as a key synthetic intermediate or active pharmaceutical ingredient (API) in advanced research and development. It is primarily sought by pharmaceutical, agrochemical, and advanced material scientists for creating novel molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or insecticides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Chemical Biology Probe: Acts as a scaffold or inhibitor in biochemical assays to study enzyme function and signal transduction pathways.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or specialty polymers due to its conjugated system and fluorine content.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocyclic frameworks via various condensation and cyclization reactions.

Basic Information

Product Name	1,3-Dimethyl-5-[3-(Trifluoromethyl)Benzoyl]-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	866156-21-0
Molecular Formula	C14H11F3N2O4
Molecular Weight	328.25 g/mol
Synonyms	5-(3-Trifluoromethylbenzoyl)-1,3-dimethylbarbituric Acid; 1,3-Dimethyl-5-(3-trifluoromethylbenzoyl)barbituric Acid; 5-(3-Trifluoromethylbenzoyl)-1,3-dimethyl-2,4,6-pyrimidinetrione; 1,3-Dimethyl-5-(α-oxo-3-(trifluoromethyl)benzyl)barbituric Acid; 866156-21-0; 3-(Trifluoromethyl)benzoyl-1,3-dimethylbarbituric Acid Derivative
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-5-[3-(Trifluoromethyl)Benzoyl]-2,4,6(1H,3H,5H)-Pyrimidinetrione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.