Description

1-(2-Amino-6-Chloro-Pyrimidin-4-Yl)-Piperidine-4-Carboxylic Acid Methyl Ester is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a chloropyrimidine and a piperidine ester moiety, makes it a versatile intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology & Proteomics: Serves as a scaffold or linker molecule for creating chemical probes to study enzyme function and protein interactions.
• Material Science Research: Potential building block for advanced organic materials and ligands in catalytic systems due to its rigid, nitrogen-rich structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	1-(2-Amino-6-Chloro-Pyrimidin-4-Yl)-Piperidine-4-Carboxylic Acid Methyl Ester
CAS No.	866050-01-3
Molecular Formula	C11H15ClN4O2
Molecular Weight	270.72 g/mol
Synonyms	Methyl 1-(2-amino-6-chloropyrimidin-4-yl)piperidine-4-carboxylate; 4-Piperidinecarboxylic acid, 1-(2-amino-6-chloro-4-pyrimidinyl)-, methyl ester; 1-(2-Amino-6-chloro-4-pyrimidinyl)-4-piperidinecarboxylic acid methyl ester; Methyl 1-(2-amino-6-chloro-4-pyrimidinyl)piperidine-4-carboxylate; 866050-01-3; 1-(2-Amino-6-chloro-pyrimidin-4-yl)-piperidine-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of 1-(2-Amino-6-Chloro-Pyrimidin-4-Yl)-Piperidine-4-Carboxylic Acid Methyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.