Description

Methyl 7-Amino-3-(4-Chlorophenyl)Pyrazolo[1,5-A]Pyrimidine-6-Carboxylate is a high-purity, heterocyclic organic compound that serves as a critical advanced intermediate in modern pharmaceutical synthesis. Its value lies in its precise molecular architecture, which provides a versatile scaffold for constructing complex active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries, particularly those focused on developing novel therapeutic agents.

Application

This specialized pyrazolopyrimidine derivative is a key building block in the synthesis of complex molecules. Its primary applications include:

• Pharmaceutical Intermediate: Core scaffold for the research and development of potential drug candidates targeting various diseases.
• API Synthesis: Used in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs), particularly in kinase inhibitor programs.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, or insecticides.
• Chemical Biology: Utilized as a probe or tool compound in biochemical and pharmacological research to study enzyme function and signaling pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule construction.

Basic Information

Product Name	Methyl 7-Amino-3-(4-Chlorophenyl)Pyrazolo[1,5-A]Pyrimidine-6-Carboxylate
CAS No.	866049-89-0
Molecular Formula	C14H11ClN4O2
Molecular Weight	302.71 g/mol
Synonyms	Methyl 7-amino-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate; 7-Amino-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid methyl ester; Methyl 7-amino-3-(p-chlorophenyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate; 3-(4-Chlorophenyl)-7-aminopyrazolo[1,5-a]pyrimidine-6-carboxylic acid methyl ester; 866049-89-0; Pyrazolo[1,5-a]pyrimidine-6-carboxylate, methyl 7-amino-3-(4-chlorophenyl)-
EINECS	Contact for details

Quality Control

Our Methyl 7-Amino-3-(4-Chlorophenyl)Pyrazolo[1,5-A]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.