Description

4-[3-(Trifluoromethyl)Phenyl]-2-Pyrimidinamine is a high-purity pyrimidine derivative featuring a trifluoromethylphenyl substituent. This compound serves as a critical pharmaceutical intermediate and advanced building block in organic synthesis, valued for its unique electronic and steric properties imparted by the fluorine atoms. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to the bioactivity-enhancing trifluoromethyl group.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Organic Synthesis Building Block: A versatile reagent for constructing complex heterocyclic systems in academic and industrial research settings.

Basic Information

Product Name	4-[3-(Trifluoromethyl)Phenyl]-2-Pyrimidinamine
CAS No.	866019-76-3
Molecular Formula	C11H8F3N3
Molecular Weight	239.20 g/mol
Synonyms	2-Amino-4-[3-(trifluoromethyl)phenyl]pyrimidine; 4-(3-Trifluoromethylphenyl)pyrimidin-2-amine; 2-Pyrimidinamine, 4-[3-(trifluoromethyl)phenyl]-; α,α,α-Trifluoro-m-tolyl-2-aminopyrimidine; 4-(3-(Trifluoromethyl)phenyl)pyrimidin-2-amine; 4-(α,α,α-Trifluoro-m-tolyl)-2-pyrimidinamine
EINECS	Contact for details

Quality Control

Our 4-[3-(Trifluoromethyl)Phenyl]-2-Pyrimidinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.