Description

5-[3-(Trifluoromethyl)Phenyl]Pyrazolo[1,5-A]Pyrimidine-3-Carbonitrile is a high-value, heterocyclic organic compound featuring a pyrazolopyrimidine core substituted with a trifluoromethylphenyl group and a nitrile functionality. This molecular structure makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Medicinal Chemistry Building Block: Used in high-throughput screening and combinatorial chemistry for the discovery of new bioactive molecules.
• Agrochemical Research: Serves as a core structure for developing new pesticides and herbicides, leveraging the biological activity of the pyrazolopyrimidine scaffold.
• Material Science: Investigated for use in organic electronics and as a component in specialty polymers due to its aromatic and electron-deficient properties.
• Chemical Synthesis: Employed in organic synthesis for constructing complex heterocyclic systems for various R&D applications.

Basic Information

Product Name	5-[3-(Trifluoromethyl)Phenyl]Pyrazolo[1,5-A]Pyrimidine-3-Carbonitrile
CAS No.	866019-49-0
Molecular Formula	C14H7F3N4
Molecular Weight	288.23 g/mol
Synonyms	5-[3-(Trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carbonitrile; 5-(3-(Trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile; 866019-49-0; Pyrazolo[1,5-a]pyrimidine-3-carbonitrile, 5-[3-(trifluoromethyl)phenyl]-; 5-(3-Trifluoromethylphenyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile; 5-(α,α,α-Trifluoro-m-tolyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 5-[3-(Trifluoromethyl)Phenyl]Pyrazolo[1,5-A]Pyrimidine-3-Carbonitrile adheres to stringent in-process controls and final batch analysis to ensure high purity and consistency. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.