Description

4-(5-Chloro-2-Thienyl)-2-Pyrimidinethiol is a high-purity heterocyclic building block and key synthetic intermediate. This compound is valued for its unique molecular architecture, which combines thiophene and pyrimidine pharmacophores, making it a versatile scaffold in advanced organic synthesis. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials, such as semiconductors and conductive polymers, due to its conjugated system.
• Chemical Synthesis: Acts as a versatile reagent for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for metal catalysis and coordination chemistry.

Basic Information

Product Name	4-(5-Chloro-2-Thienyl)-2-Pyrimidinethiol
CAS No.	866019-24-1
Molecular Formula	C8H5ClN2S2
Molecular Weight	228.72 g/mol
Synonyms	4-(5-Chlorothiophen-2-yl)pyrimidine-2-thiol; 2-Mercapto-4-(5-chloro-2-thienyl)pyrimidine; 4-(5-Chloro-2-thienyl)-2(1H)-pyrimidinethione; 5-Chloro-2-(2-mercaptopyrimidin-4-yl)thiophene; 866019-24-1; 4-(5-Chloro-thiophen-2-yl)-2-mercapto-pyrimidine
EINECS	Contact for details

Quality Control

Our production of 4-(5-Chloro-2-Thienyl)-2-Pyrimidinethiol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.