Description

(R)-1-(2-(Trifluoromethyl)Phenyl)Ethanamine Hydrochloride is a high-purity chiral amine building block essential for advanced pharmaceutical synthesis. Its value lies in the combination of a stereogenic center and a trifluoromethyl group, which are critical for modulating the biological activity, metabolic stability, and lipophilicity of drug candidates. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides where the trifluoromethyl group enhances efficacy and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Research: Employed as a molecular probe or building block for studying enzyme interactions and biological pathways.
• Material Science: Potential monomer or modifier in the synthesis of specialty polymers with unique optical or surface properties.

Basic Information

Product Name	(R)-1-(2-(Trifluoromethyl)Phenyl)Ethanamine Hydrochloride
CAS No.	865815-07-2
Molecular Formula	C9H11ClF3N
Molecular Weight	225.64 g/mol
Synonyms	(R)-1-[2-(Trifluoromethyl)phenyl]ethanamine hydrochloride; (R)-α-Methyl-2-(trifluoromethyl)benzylamine hydrochloride; (R)-1-(2-Trifluoromethylphenyl)ethylamine HCl; (R)-2-(Trifluoromethyl)phenethylamine hydrochloride; (R)-TFMPEA HCl; (1R)-1-[2-(Trifluoromethyl)phenyl]ethan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(2-(Trifluoromethyl)Phenyl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.