Description

2-[(6-Chloro-3,4-Dihydro-3-Methyl-2,4-Dioxo-1(2H)-Pyrimidinyl)Methyl]Benzonitrile is a high-value pharmaceutical intermediate and advanced chemical building block characterized by its fused pyrimidinone and benzonitrile structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting various therapeutic areas. It is primarily sought after by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers requiring high-purity, structurally complex intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those with uracil or pyrimidinone-based scaffolds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators that utilize heterocyclic chemistry.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study enzyme inhibition or biological pathways.
• Organic Synthesis Building Block: Utilized in complex multi-step organic syntheses due to its reactive chloro and cyano functional groups.
• Material Science Research: Potential monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	2-[(6-Chloro-3,4-Dihydro-3-Methyl-2,4-Dioxo-1(2H)-Pyrimidinyl)Methyl]Benzonitrile
CAS No.	865758-96-9
Molecular Formula	C13H10ClN3O2
Molecular Weight	275.69 g/mol
Synonyms	6-Chloro-3-methyl-1-[(2-cyanophenyl)methyl]uracil; 1-[(2-Cyanobenzyl)]-6-chloro-3-methyluracil; 6-Chloro-3-methyl-1-(2-cyanobenzyl)uracil; 2-[(6-Chloro-3-methyl-2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)methyl]benzonitrile; 1-(2-Cyanobenzyl)-6-chloro-3-methyl-2,4(1H,3H)-pyrimidinedione; Uracil, 6-chloro-3-methyl-1-[(2-cyanophenyl)methyl]-; Benzonitrile, 2-[(6-chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-
EINECS	Contact for details

Quality Control

Our production of 2-[(6-Chloro-3,4-Dihydro-3-Methyl-2,4-Dioxo-1(2H)-Pyrimidinyl)Methyl]Benzonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All material is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We can supply material compliant with ISO 9001 quality standards, and our processes are designed to meet the exacting requirements of pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.