Description

4-n-Boc-Amino-3-Fluorobenzaldehyde is a high-purity, protected amino aldehyde building block of significant importance in advanced organic synthesis. This compound is specifically engineered to serve as a critical intermediate in the development of complex pharmaceutical molecules and bioactive compounds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing fluorinated aromatic systems and protected amine functionalities.
• Peptidomimetic Synthesis: Used in the construction of non-peptide scaffolds that mimic peptides, which are valuable in drug discovery for improved metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides where the fluorine atom and aldehyde group impart specific biological activity and physical properties.
• Material Science Precursor: Can be utilized in the synthesis of functionalized polymers and advanced organic materials with tailored electronic or optical properties.
• Chemical Biology Probes: Acts as a building block for creating fluorescent tags, affinity labels, and other molecular probes for biological research.

Basic Information

Product Name	4-n-Boc-Amino-3-Fluorobenzaldehyde
CAS No.	865450-09-5
Molecular Formula	C₁₂H₁₄FNO₃
Molecular Weight	239.24 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amino]-3-fluorobenzaldehyde; 3-Fluoro-4-[(tert-butoxycarbonyl)amino]benzaldehyde; 4-(Boc-amino)-3-fluorobenzaldehyde; Boc-4-Amino-3-fluorobenzaldehyde; tert-Butyl (4-formyl-2-fluorophenyl)carbamate; 4-(tert-Butoxycarbonylamino)-3-fluorobenzaldehyde; 4-N-Boc-amino-3-fluorobenzaldehyde
EINECS	Contact for details

Quality Control

Our 4-n-Boc-Amino-3-Fluorobenzaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including research and cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.