Description

4-Chloro-5-Methyl-Imidazo[5,1-F][1,2,4]Triazine is a high-purity, advanced pharmaceutical intermediate belonging to the fused heterocyclic triazine class. This compound is of significant commercial importance for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides and fungicides with novel modes of action.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and organic electronic materials.
• Academic & Contract Research: Employed in medicinal chemistry programs and structure-activity relationship (SAR) studies within university and CRO laboratories.
• Process Chemistry: Utilized for scale-up and optimization of synthetic routes in pilot plants and commercial manufacturing.

Basic Information

Product Name	4-Chloro-5-Methyl-Imidazo[5,1-F][1,2,4]Triazine
CAS No.	865444-79-7
Molecular Formula	C6H5ClN4
Molecular Weight	168.58 g/mol
Synonyms	4-Chloro-5-methylimidazo[5,1-f][1,2,4]triazine; 5-Methyl-4-chloroimidazo[5,1-f][1,2,4]triazine; Imidazo[5,1-f][1,2,4]triazine, 4-chloro-5-methyl-; 865444-79-7; 4-Chloro-5-methyl-[1,2,4]triazolo[1,5-f]purine (alternative naming); CTK8G6685; ZINC000253049793; AKOS040759176
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Methyl-Imidazo[5,1-F][1,2,4]Triazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical development and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.