Description

2,4-Dichloro-6-Methoxy-5-Phenyl-Pyrimidine is a high-purity, multi-functional pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its versatile halogenated and methoxylated structure, which enables precise molecular modifications for creating complex, high-value compounds. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging its halogenated pyrimidine core.
• Material Science Research: Serves as a precursor for organic electronic materials and liquid crystals due to its phenyl-pyrimidine structure.
• Chemical Research & Development: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex substituents.
• Custom Synthesis: A foundational block for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.

Basic Information

Product Name	2,4-Dichloro-6-Methoxy-5-Phenyl-Pyrimidine
CAS No.	864655-18-5
Molecular Formula	C11H8Cl2N2O
Molecular Weight	255.10 g/mol
Synonyms	5-Phenyl-2,4-dichloro-6-methoxypyrimidine; 2,4-Dichloro-6-methoxy-5-phenylpyrimidine; 6-Methoxy-2,4-dichloro-5-phenylpyrimidine; 5-Phenyl-2,4-dichloro-6-methoxypyrimidine; 864655-18-5; Pyrimidine, 2,4-dichloro-6-methoxy-5-phenyl-
EINECS	Contact for details

Quality Control

Every batch of 2,4-Dichloro-6-Methoxy-5-Phenyl-Pyrimidine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, GC, NMR, and other relevant techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.