Description

[1-(4-Fluorobenzyl)Pyrrolidin-2-Yl]Methanol is a high-purity fluorinated pyrrolidine derivative, a crucial building block in modern synthetic chemistry. This compound matters for its role as a versatile chiral intermediate, enabling the synthesis of complex molecules with high stereochemical control. Pharmaceutical R&D and fine chemical manufacturers need it for developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorobenzyl moiety can enhance biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for high-value, complex organic molecules.
• Academic & Industrial Research: A valuable tool compound for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	[1-(4-Fluorobenzyl)Pyrrolidin-2-Yl]Methanol
CAS No.	864415-55-4
Molecular Formula	C12H16FNO
Molecular Weight	209.26 g/mol
Synonyms	2-(Hydroxymethyl)-1-[(4-fluorophenyl)methyl]pyrrolidine; 1-[(4-Fluorophenyl)methyl]-2-pyrrolidinemethanol; (1-[(4-Fluorobenzyl)]-2-pyrrolidinyl)methanol; 1-(4-Fluorobenzyl)-2-pyrrolidinemethanol; 1-(4-Fluorobenzyl)pyrrolidine-2-methanol; 1-(4-Fluorobenzyl)-2-(hydroxymethyl)pyrrolidine; 864415-55-4; 1-(4-Fluorobenzyl)-2-pyrrolidinylmethanol
EINECS	Contact for details

Quality Control

Our [1-(4-Fluorobenzyl)Pyrrolidin-2-Yl]Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.