Description

4,6-Bis[3-(Trifluoromethoxy)Phenoxy]Pyrimidin-5-Amine is a high-value, fluorinated pyrimidine derivative that serves as a critical building block in advanced chemical synthesis. Its molecular structure, featuring trifluoromethoxy phenoxy groups, imparts unique electronic and steric properties essential for developing novel materials and active compounds. This intermediate is primarily sought by R&D and process development teams in the pharmaceutical and agrochemical sectors for creating next-generation products.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in developing novel herbicides and pesticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Material Science: Building block for advanced polymers and liquid crystals, leveraging its aromatic and fluorine content for improved thermal and chemical resistance.
• Organic Electronics: Potential component in the development of organic light-emitting diodes (OLEDs) and semiconductors due to its electron-deficient pyrimidine core.
• Chemical Synthesis: Versatile intermediate for further functionalization, enabling the creation of complex molecular libraries for high-throughput screening.

Basic Information

Product Name	4,6-Bis[3-(Trifluoromethoxy)Phenoxy]Pyrimidin-5-Amine
CAS No.	864371-12-0
Molecular Formula	C18H12F6N3O4
Molecular Weight	448.30 g/mol
Synonyms	5-Amino-4,6-bis[3-(trifluoromethoxy)phenoxy]pyrimidine; 4,6-Bis(3-trifluoromethoxyphenoxy)pyrimidin-5-amine; 864371-12-0; 5-Pyrimidinamine, 4,6-bis[3-(trifluoromethoxy)phenoxy]-; 4,6-Bis(3-(trifluoromethoxy)phenoxy)pyrimidin-5-amine
EINECS	Contact for details

Quality Control

Our production of 4,6-Bis[3-(Trifluoromethoxy)Phenoxy]Pyrimidin-5-Amine adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, with specifications tailored to meet the exacting requirements of research and commercial-scale synthesis. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% to ≥98% by HPLC), residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.