Description

2,4-Dihydroxyquinazoline-7-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile precursor in the development of complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on kinase inhibitors, anticancer agents, and other biologically active nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of quinazoline-based drug candidates, including potential tyrosine kinase inhibitors and anticancer agents.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Building Block: Serves as a versatile precursor for constructing complex polycyclic systems and functionalized quinazolines via its reactive nitrile and hydroxyl groups.
• Material Science Research: Investigated as a monomer or ligand for creating functional organic materials, such as metal-organic frameworks (MOFs) or polymers with specific electronic properties.
• Biochemical Tool Compound: Utilized in academic and industrial research to study enzyme inhibition and modulate biological pathways.

Basic Information

Product Name	2,4-Dihydroxyquinazoline-7-Carbonitrile
CAS No.	864292-20-6
Molecular Formula	C9H5N3O2
Molecular Weight	187.16 g/mol
Synonyms	7-Cyano-2,4(1H,3H)-quinazolinedione; 2,4-Dihydroxy-7-cyanoquinazoline; 7-Cyano-2,4-dihydroxyquinazoline; 2,4(1H,3H)-Quinazolinedione, 7-cyano-; 864292-20-6; Quinazoline-7-carbonitrile, 2,4-dihydroxy-
EINECS	Contact for details

Quality Control

Our 2,4-Dihydroxyquinazoline-7-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.