Description

5-Pyrimidinecarboxylic Acid, 2-(Phenylamino)-, Ethyl Ester is a high-purity, synthetic organic compound belonging to the pyrimidine class, a core heterocyclic structure of significant pharmaceutical interest. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. The consistent quality and reliable supply of this intermediate are essential for accelerating drug discovery and development pipelines.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new herbicides, fungicides, or insecticides.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom synthesis of complex, specialty molecules under cGMP or research-grade conditions.

Basic Information

Item	Detail
Product Name	5-Pyrimidinecarboxylic Acid, 2-(Phenylamino)-, Ethyl Ester
CAS No.	864172-93-0
Molecular Formula	C13H13N3O2
Molecular Weight	243.26 g/mol
Synonyms	Ethyl 2-(Phenylamino)pyrimidine-5-carboxylate; 2-Anilino-5-pyrimidinecarboxylic Acid Ethyl Ester; 2-(Phenylamino)pyrimidine-5-carboxylic Acid Ethyl Ester; Ethyl 2-Anilinopyrimidine-5-carboxylate; 864172-93-0; 2-(Phenylamino)-5-pyrimidinecarboxylic acid ethyl ester; 5-Pyrimidinecarboxylic acid, 2-(phenylamino)-, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of 5-Pyrimidinecarboxylic Acid, 2-(Phenylamino)-, Ethyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment. Our quality commitment supports applications from early-stage research to cGMP-compliant advanced intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.