Description

2-Chloro-3-Fluorophenol is a versatile halogenated phenol derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated phenols.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials and organic light-emitting diodes.
• Polymer Modification: Acts as a monomer or functionalizing agent to introduce specific halogen and hydroxyl groups into polymer chains, altering material properties.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of complex colorants and specialty dyes.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations for carbon-carbon and carbon-heteroatom bond formation.

Basic Information

Product Name	2-Chloro-3-Fluorophenol
CAS No.	863870-86-4
Molecular Formula	C6H4ClFO
Molecular Weight	146.55 g/mol
Synonyms	2-Chloro-3-fluorophenol; 3-Fluoro-2-chlorophenol; Phenol, 2-chloro-3-fluoro-; 1-Chloro-2-fluoro-6-hydroxybenzene; o-Chloro-m-fluorophenol; 2-Chloro-3-fluoro-1-hydroxybenzene; 863870-86-4
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Fluorophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.