Description

Ethyl 4-tert-Butyl-2-Chloropyrimidine-5-Carboxylate is a high-value pyrimidine derivative, a crucial building block in advanced organic synthesis. Its significance lies in its role as a versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology: Employed in the synthesis of molecular probes and labeled compounds for biochemical and pharmacological studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring functionalized pyrimidine scaffolds.

Basic Information

Product Name	Ethyl 4-tert-Butyl-2-Chloropyrimidine-5-Carboxylate
CAS No.	863323-33-5
Molecular Formula	C11H15ClN2O2
Molecular Weight	242.70 g/mol
Synonyms	Ethyl 4-(tert-butyl)-2-chloropyrimidine-5-carboxylate; 2-Chloro-4-tert-butylpyrimidine-5-carboxylic acid ethyl ester; 5-Carbethoxy-4-tert-butyl-2-chloropyrimidine; 4-tert-Butyl-2-chloro-5-pyrimidinecarboxylic acid ethyl ester; 863323-33-5; 2-Chloro-4-(1,1-dimethylethyl)-5-pyrimidinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-tert-Butyl-2-Chloropyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.