Description

2-(Ethylsulfonyl)-4-(3-Methoxyphenyl)-6-(Trifluoromethyl)Pyrimidine is a high-value, multi-functional pyrimidine derivative characterized by its ethylsulfonyl and trifluoromethyl substituents. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry, enabling the development of novel active ingredients. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for its unique structural features that impart desirable biological and physicochemical properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioactivity and environmental stability.
• Material Science Precursor: Serves as a monomer or functional additive in the synthesis of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular scaffold in drug discovery platforms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP or ISO standards for clinical trial material supply.

Basic Information

Product Name	2-(Ethylsulfonyl)-4-(3-Methoxyphenyl)-6-(Trifluoromethyl)Pyrimidine
CAS No.	862785-73-7
Molecular Formula	C14H13F3N2O3S
Molecular Weight	346.33 g/mol
Synonyms	4-(3-Methoxyphenyl)-6-(trifluoromethyl)-2-(ethylsulfonyl)pyrimidine; 2-Ethylsulfonyl-4-(3-methoxyphenyl)-6-trifluoromethylpyrimidine; 6-(Trifluoromethyl)-4-(3-methoxyphenyl)-2-(ethylsulfonyl)pyrimidine; Pyrimidine, 2-(ethylsulfonyl)-4-(3-methoxyphenyl)-6-(trifluoromethyl)-; CAS 862785-73-7
EINECS	Contact for details

Quality Control

Our production of 2-(Ethylsulfonyl)-4-(3-Methoxyphenyl)-6-(Trifluoromethyl)Pyrimidine adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all specified parameters. We support cGMP and ISO 9001 compliant manufacturing for pharmaceutical-grade requirements, and specifications can be tailored to meet your specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.