Description

3-Iodo-1-Isopropyl-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is a high-value, halogenated heterocyclic building block of significant interest in medicinal chemistry and advanced organic synthesis. Its core structure serves as a versatile scaffold for the development of targeted small molecule inhibitors, particularly in oncology research. This compound is essential for pharmaceutical R&D teams and fine chemical manufacturers engaged in creating novel kinase inhibitors and other therapeutic agents. We supply this critical intermediate with a focus on high purity, batch-to-batch consistency, and reliable global logistics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent and selective kinase inhibitors targeting various cancer pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Probe Development: Employed in the creation of tool compounds for studying specific enzyme functions and cellular signaling mechanisms.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex heterocyclic molecules in custom synthesis and contract manufacturing.
• Academic Research: Utilized in university and institutional labs for pioneering research in organic synthesis methodologies and bioorganic chemistry.

Basic Information

Product Name	3-Iodo-1-Isopropyl-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine
CAS No.	862730-04-9
Molecular Formula	C8H10IN5
Molecular Weight	303.10 g/mol
Synonyms	3-Iodo-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-iodo-1-(1-methylethyl)-; 862730-04-9; 3-Iodo-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine; 4-Amino-3-iodo-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Every batch of 3-Iodo-1-Isopropyl-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is manufactured and tested under a strict quality management system. We employ advanced analytical techniques, including HPLC, NMR, and MS, to ensure identity, purity, and conformity to customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.