Description

{[4-(5-Methylthien-2-Yl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Acetic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure incorporating a thienyl and a trifluoromethylated pyrimidine core. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular modifications. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing next-generation compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the pyrimidine-thiophene scaffold.
• Chemical Synthesis Building Block: Serves as a versatile synthon for constructing complex molecules in medicinal chemistry and material science research.
• Life Science Reagent: Employed in biochemical research as a tool compound for studying enzyme inhibition and receptor binding.

Basic Information

Product Name	{[4-(5-Methylthien-2-Yl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Acetic Acid
CAS No.	862679-50-3
Molecular Formula	C12H9F3N2O2S2
Molecular Weight	334.33 g/mol
Synonyms	2-({[4-(5-Methyl-2-thienyl)-6-(trifluoromethyl)-2-pyrimidinyl]thio})acetic Acid; [4-(5-Methylthiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfanylacetic Acid; 2-[[4-(5-Methyl-2-thienyl)-6-(trifluoromethyl)-2-pyrimidinyl]thio]acetic Acid; CAS 862679-50-3; 2-({4-(5-Methylthiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl}thio)acetic Acid
EINECS	Contact for details

Quality Control

Our {[4-(5-Methylthien-2-Yl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.