Description

1-[4-(Difluoromethyl)-6-(2-Furyl)Pyrimidin-2-Yl]Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure incorporating pyrimidine, piperidine, and furan moieties. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Key building block in the research and synthesis of novel pharmaceutical compounds targeting various disease pathways.
• Advanced intermediate for the development of kinase inhibitors and other small-molecule therapeutics.
• Used in medicinal chemistry research for structure-activity relationship (SAR) studies and lead optimization.
• Precursor in the custom synthesis of complex molecules for preclinical and clinical trial materials.
• Valuable reference standard for analytical method development and quality control in API manufacturing.
• Starting material for the synthesis of specialized agrochemicals and other performance chemicals requiring a difluoromethylpyrimidine scaffold.

Basic Information

Product Name	1-[4-(Difluoromethyl)-6-(2-Furyl)Pyrimidin-2-Yl]Piperidine-4-Carboxylic Acid
CAS No.	862659-10-7
Molecular Formula	C15H15F2N3O3
Molecular Weight	323.30 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-[4-(difluoromethyl)-6-(2-furanyl)-2-pyrimidinyl]-; 1-(4-(Difluoromethyl)-6-(furan-2-yl)pyrimidin-2-yl)piperidine-4-carboxylic acid; 862659-10-7; UNII-9V8C6K3W0I; 9V8C6K3W0I; AKOS025147065; AS-87233; CS-0476640; FT-0773393
EINECS	Contact for details

Quality Control

Our production of 1-[4-(Difluoromethyl)-6-(2-Furyl)Pyrimidin-2-Yl]Piperidine-4-Carboxylic Acid adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity. The material is manufactured and tested in facilities that follow cGMP guidelines where applicable. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with all applicable regulations for chemicals.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Single Maximum Impurity	≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.