Description

1-[4-Cyclopropyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrimidine-piperidine hybrid structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of novel drug candidates, especially in kinase inhibitor programs.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides due to its bioactive pyrimidine core.
• Chemical Biology & Proteomics: Acts as a versatile scaffold or linker for creating chemical probes and tool compounds for target identification and validation.
• Material Science: Potential precursor for the synthesis of specialty polymers and ligands with specific electronic properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	1-[4-Cyclopropyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Piperidine-4-Carboxylic Acid
CAS No.	862652-23-1
Molecular Formula	C14H16F3N3O2
Molecular Weight	315.29 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-[4-cyclopropyl-6-(trifluoromethyl)-2-pyrimidinyl]-; 1-(4-Cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl)piperidine-4-carboxylic acid; 862652-23-1; 1-[4-Cyclopropyl-6-(trifluoromethyl)-2-pyrimidinyl]piperidine-4-carboxylic acid; 4-Carboxy-1-[4-cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl]piperidine
EINECS	Contact for details

Quality Control

Our production of 1-[4-Cyclopropyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Piperidine-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality systems are designed to support development and commercial projects requiring reliable and traceable material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.