Description

[4-(4-Bromo-Phenyl)-6-Difluoromethyl-Pyrimidin-2-Yl]-Hydrazine is a high-purity, specialized pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring bromo-phenyl and difluoromethyl substituents, makes it a valuable precursor for constructing complex heterocyclic systems with tailored electronic and steric properties. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyrimidine core.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring complex, fluorinated heterocyclic architectures.

Basic Information

Product Name	[4-(4-Bromo-Phenyl)-6-Difluoromethyl-Pyrimidin-2-Yl]-Hydrazine
CAS No.	862652-02-6
Molecular Formula	C11H9BrF2N4
Molecular Weight	315.12 g/mol
Synonyms	4-(4-Bromophenyl)-6-(difluoromethyl)-2-pyrimidinylhydrazine; (4-(4-Bromophenyl)-6-(difluoromethyl)pyrimidin-2-yl)hydrazine; 2-Hydrazinyl-4-(4-bromophenyl)-6-(difluoromethyl)pyrimidine; 4-(4-Bromo-phenyl)-6-difluoromethyl-pyrimidin-2-yl-hydrazine; 862652-02-6; Bromo-difluoromethyl-pyrimidinyl hydrazine
EINECS	Contact for details

Quality Control

Every batch of [4-(4-Bromo-Phenyl)-6-Difluoromethyl-Pyrimidin-2-Yl]-Hydrazine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.