Description

2-Hydrazino-4-(3-Methoxyphenyl)-6-(Trifluoromethyl)Pyrimidine is a specialized heterocyclic building block featuring a hydrazino substituent and a trifluoromethyl group, which are key functional motifs in modern synthetic chemistry. This compound matters for its role as a critical intermediate in the development of high-value, complex molecules, particularly within the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, where its unique structure enables the synthesis of compounds with targeted biological activity and improved physicochemical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl and pyrimidine groups.
• Material Science: Serves as a building block for advanced organic materials, such as ligands for catalysis or components in organic electronic devices.
• Chemical Biology & Proteomics: Employed in the design of chemical probes and affinity tags for studying protein function and interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	2-Hydrazino-4-(3-Methoxyphenyl)-6-(Trifluoromethyl)Pyrimidine
CAS No.	861440-89-3
Molecular Formula	C12H11F3N4O
Molecular Weight	284.24 g/mol
Synonyms	2-Hydrazinyl-4-(3-methoxyphenyl)-6-(trifluoromethyl)pyrimidine; 4-(3-Methoxyphenyl)-6-(trifluoromethyl)-2-pyrimidinylhydrazine; 2-Hydrazino-4-(3-methoxyphenyl)-6-trifluoromethylpyrimidine; 6-(Trifluoromethyl)-4-(3-methoxyphenyl)-2-pyrimidinylhydrazine; 861440-89-3; 4-(m-Methoxyphenyl)-6-(trifluoromethyl)-2-hydrazinopyrimidine
EINECS	Contact for details

Quality Control

Our 2-Hydrazino-4-(3-Methoxyphenyl)-6-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and quality assurance for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its property of being easily oxidized, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.