Description

[4-(2-Methoxy-Phenyl)-6-Trifluoromethyl-Pyrimidin-2-Yl]-Hydrazine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyrimidine-hydrazine structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Serves as a precursor in the development of new-generation pesticides and herbicides, leveraging the biological activity of the trifluoromethylpyrimidine moiety.
• Chemical Synthesis: Used in organic synthesis for constructing complex heterocyclic compounds in medicinal chemistry programs.
• Material Science Research: Investigated for potential applications in creating specialty polymers or functional materials with specific electronic properties.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and exploring new chemical reactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP guidelines.

Basic Information

Product Name	[4-(2-Methoxy-Phenyl)-6-Trifluoromethyl-Pyrimidin-2-Yl]-Hydrazine
CAS No.	861440-88-2
Molecular Formula	C12H11F3N4O
Molecular Weight	284.24 g/mol
Synonyms	4-(2-Methoxyphenyl)-6-(trifluoromethyl)-2-pyrimidinylhydrazine; (4-(2-Methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl)hydrazine; 2-Hydrazinyl-4-(2-methoxyphenyl)-6-(trifluoromethyl)pyrimidine; 4-(2-Methoxy-phenyl)-6-trifluoromethyl-pyrimidin-2-yl-hydrazine; 861440-88-2; Hydrazine, [4-(2-methoxyphenyl)-6-(trifluoromethyl)-2-pyrimidinyl]-; 6-Trifluoromethyl-4-(2-methoxyphenyl)pyrimidin-2-ylhydrazine
EINECS	Contact for details

Quality Control

Our [4-(2-Methoxy-Phenyl)-6-Trifluoromethyl-Pyrimidin-2-Yl]-Hydrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development under ICH guidelines and can supply material suitable for research use under current Good Manufacturing Practice (cGMP) conditions for advanced projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider storing under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.