Description

4-(7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidin-5-Yl)-Phenol is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure containing a phenol and a trifluoromethyl group. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing new chemical entities.

Application

• Key building block for the synthesis of novel pharmaceutical candidates, especially kinase inhibitors.
• Advanced intermediate in the development of agrochemicals, such as herbicides and fungicides.
• Precursor for functional materials and organic electronic components.
• Versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Used in custom synthesis and contract manufacturing for specialized chemical projects.
• Starting material for the preparation of fluorinated compounds with enhanced metabolic stability and bioavailability.

Basic Information

Product Name	4-(7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidin-5-Yl)-Phenol
CAS No.	861435-10-1
Molecular Formula	C13H7F3N3O
Molecular Weight	278.21 g/mol
Synonyms	5-(4-Hydroxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine; 4-(7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl)phenol; Phenol, 4-[7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]-; 861435-10-1; 5-(4-Hydroxy-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine; 4-(7-Trifluoromethylpyrazolo[1,5-a]pyrimidin-5-yl)phenol
EINECS	Contact for details

Quality Control

Our production of 4-(7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidin-5-Yl)-Phenol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured in a GMP-compliant environment, with quality assurance processes aligned with ICH guidelines. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) documenting all critical specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.