Description

([4-Cyclopropyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio)Acetic Acid is a high-value pyrimidine derivative featuring a cyclopropyl and a trifluoromethyl group, making it a versatile synthetic intermediate. This compound is critical for research and development in advanced organic synthesis, particularly for constructing complex molecules with tailored biological and physical properties. It is primarily sought by pharmaceutical, agrochemical, and specialty chemical manufacturers for applications in drug discovery and crop protection agent development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting specific enzyme inhibition.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine core.
• Chemical Research: Acts as a precursor in medicinal chemistry and material science for creating libraries of compounds for high-throughput screening.
• Ligand and Catalyst Development: Employed in the design of specialized ligands for metal catalysis or as a scaffold for functional materials.

Basic Information

Product Name	([4-Cyclopropyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio)Acetic Acid
CAS No.	861434-52-8
Molecular Formula	C10H9F3N2O2S
Molecular Weight	278.25 g/mol
Synonyms	2-[(4-Cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl)thio]acetic acid; Acetic acid, 2-[[4-cyclopropyl-6-(trifluoromethyl)-2-pyrimidinyl]thio]-; 2-((4-Cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl)thio)acetic acid; ([4-Cyclopropyl-6-(Trifluoromethyl)-2-Pyrimidinyl]Thio)Acetic Acid; 861434-52-8; 2-({4-cyclopropyl-6-[(trifluoromethyl)]pyrimidin-2-yl}sulfanyl)acetic acid
EINECS	Contact for details

Quality Control

Our production of ([4-Cyclopropyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio)Acetic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.